Successful treatment of empyema thoracis with human recombinant deoxyribonuclease

被引：43

作者：

Simpson, G

Roomes, D

Reeves, B

机构：

[1] Cairns Base Hosp, Dept Thorac Med, Cairns, Qld, Australia

[2] James Cook Univ N Queensland, Townsville, Qld 4811, Australia

来源：

THORAX | 2003年 / 58卷 / 04期

关键词：

D O I：

10.1136/thorax.58.4.365

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Fibrinolytic enzymes, particularly streptokinase, are now widely used to treat empyema thoracis. Recent in vitro evidence suggests that streptokinase has no effect on pus viscosity but that deoxyribonuclease (DNase) reduces the viscosity of pus. We report the first use of human recombinant DNase given intrapleurally to treat an empyema which had not resolved after standard treatment with streptokinase.

引用

页码：365 / 366

页数：2

共 7 条

[1] Controlled trial of intrapleural streptokinase in the treatment of pleural empyema and complicated parapneumonic effusions [J].