The life and times of ivermectin - a success story

被引：190

作者：

Omura, S ^{[1
]}

Crump, A ^{[1
]}

机构：

[1] Kitasato Inst, Minato Ku, Tokyo 1088642, Japan

来源：

NATURE REVIEWS MICROBIOLOGY | 2004年 / 2卷 / 12期

关键词：

D O I：

10.1038/nrmicro1048

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Since its introduction more than 20 years ago, ivermectin has proved to be one of the most successful therapeutic drugs in veterinary medicine, as well as the basis of one of the most successful public-health programmes of the past century. The drug arose from a unique international collaboration between the public and private sectors. The development process also incorporated the world's first and largest drug-donation programme and involved a unique association between governments, non-governmental organizations and industry. The drug is now being used, free of charge, in two global disease-elimination programmes that are benefiting millions of the world's poorest people.

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页码：984 / 989

页数：6

相关论文

共 53 条

[1] Randomised placebo-controlled comparison of ivermectin and albendazole alone and in combination for Wuchereria bancrofti microfilaraemia in Haitian children [J].

Addiss, DG ;

Beach, MJ ;

Streit, TG ;

Lutwick, S ;

LeConte, FH ;

Lafontant, JG ;

Hightower, AW ;

Lammie, PJ .

LANCET, 1997, 350 (9076) :480-484

[2] THE IMPACT OF 5 YEARS OF ANNUAL IVERMECTIN TREATMENT ON SKIN MICROFILARIAL LOADS IN THE ONCHOCERCIASIS FOCUS OF ASUBENDE, GHANA [J].

ALLEY, ES ;

PLAISIER, AP ;

BOATIN, BA ;

DADZIE, KY ;

REMME, J ;

ZERBO, G ;

SAMBA, EM .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1994, 88 (05) :581-584

[3]

[Anonymous], 2002, MACROLIDE ANTIBIOTIC, DOI DOI 10.1016/B978-012526451-8/50014-X

[4]

AZIZ MA, 1982, LANCET, V2, P171

[5]

AZIZ MA, 1982, LANCET, V2, P1456

[6] Selection at a P-glycoprotein gene in ivermectin- and moxidectin-selected strains of Haemonchus contortus [J].

Blackhall, WJ ;

Liu, HY ;

Xu, M ;

Prichard, RK ;

Beech, RN .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1998, 95 (02) :193-201

[7]

Burg R. W., 1989, Ivermectin and abamectin., P24

[8] AVERMECTINS, NEW FAMILY OF POTENT ANTHELMINTIC AGENTS - PRODUCING ORGANISM AND FERMENTATION [J].

BURG, RW ;

MILLER, BM ;

BAKER, EE ;

BIRNBAUM, J ;

CURRIE, SA ;

HARTMAN, R ;

KONG, YL ;

MONAGHAN, RL ;

OLSON, G ;

PUTTER, I ;

TUNAC, JB ;

WALLICK, H ;

STAPLEY, EO ;

OIWA, R ;

OMURA, S .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1979, 15 (03) :361-367

[9] Review:: The delivery of ivermectin (Mectizan®) [J].

Burnham, G ;

Mebrahtu, T .

TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2004, 9 (04) :A26-A44

[10] IVERMECTIN - A POTENT NEW ANTI-PARASITIC AGENT [J].

CAMPBELL, WC ;

FISHER, MH ;

STAPLEY, EO ;

ALBERSSCHONBERG, G ;

JACOB, TA .

SCIENCE, 1983, 221 (4613) :823-828

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