Two algorithms for non-rigid image registration and their evaluation

This paper presents two non-rigid image registration algorithms: Thirion's Demons method and its spline-based extension, and compares their performance on the task of inter-subject registration of MRI brain images. The methods are designed to be fast and derive their speed from the uncoupling of the correspondence calculation and deformation interpolation procedures, each of which are then amenable to efficient implementation. The evaluation results indicate that this uncoupling does not significantly limit the registration accuracy that can be achieved.