Vaccination against Taenia solium cysticercosis in underfed rustic pigs of Mexico:: roles of age, genetic background and antibody response

被引：22

作者：

Huerta, M

Sciutto, E

García, G

Villalobos, N

Hernández, M

Fragoso, G

Díaz, J

Díaz, A

Ramírez, R

Luna, S

García, J

Aguilar, E

Espinoza, S

Castilla, G

Bobadilla, JR

Avila, R

José, MV

Larralde, C

de Aluja, AS

机构：

[1] Univ Nacl Autonoma Mexico, Inst Invest Biomed, Dept Immunol, Mexico City 04510, DF, Mexico

[2] Univ Nacl Autonoma Mexico, Fac Med Vet & Zootecn, Mexico City 04510, DF, Mexico

[3] Benemerita Univ Autonoma Puebla, Fac Med, Puebla, Mexico

[4] Benemerita Univ Autonoma Puebla, Escuela Med Vet & Zootecn, Puebla, Mexico

[5] Inst Mexicano Seguro Social, Puebla, Mexico

来源：

VETERINARY PARASITOLOGY | 2000年 / 90卷 / 03期

关键词：

porcine cysticercosis; immunization; vaccination; antibodies; Taenia solium;

D O I：

10.1016/S0304-4017(00)00233-8

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Vaccination of pigs of mixed genetic make-up, raised as rustically as done in rural Mexico, resulted in effective protection to experimental challenge against Taenia solium cysticercosis. Maximum protection was achieved if pigs were immunized at 70 days of age. There was large variation of viable parasite load within vaccinated pigs and controls, which is suggestive of significant genetic factors influencing susceptibility, besides immunization. Our results strengthen the advisability of pig vaccination for control of T. solium cysticercosis, since it lowers the number of viable cysticerci capable of transforming into tapeworms. (C) 2000 Elsevier Science B.V. All rights reserved.

引用

页码：209 / 219

页数：11

共 20 条

[1] HELMINTH INFECTIONS OF HUMANS - MATHEMATICAL-MODELS, POPULATION-DYNAMICS, AND CONTROL [J].