Histone macroH2A1.2 is concentrated in the XY compartment of mammalian male meiotic nuclei

被引：30

作者：

Richler, C ^{[1
]}

Dhara, SK ^{[1
]}

Wahrman, J ^{[1
]}

机构：

[1] Hebrew Univ Jerusalem, Dept Genet, IL-91904 Jerusalem, Israel

来源：

CYTOGENETICS AND CELL GENETICS | 2000年 / 89卷 / 1-2期

关键词：

D O I：

10.1159/000015589

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

We show here that histone macroH2A1.2 concentrates at the transcriptionally silent XY body, normally being formed during male meiosis in the mouse. A similar accumulation has earlier been observed on the inactive X chromosomes of somatic adult female mammalian cells by Costanzi and Pehrson (1998). This correspondence in the nature of heterochromatinization of the X chromosomes in males and females adds another property of X chromosome inactivation that is shared by males and females at different phases of their life cycle. Copyright(C)2000S.KargerAG,Basel.

引用

页码：118 / 120

页数：3

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