Genes and the response to drugs

被引:53
作者
Caraco, Y [1 ]
机构
[1] Hadassah Univ Hosp, Div Med, IL-91120 Jerusalem, Israel
关键词
D O I
10.1056/NEJMe048278
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:2867 / 2869
页数:3
相关论文
共 12 条
[1]  
Caraco Y, 1996, J PHARMACOL EXP THER, V278, P1165
[2]   MU RECEPTOR-BINDING OF SOME COMMONLY USED OPIOIDS AND THEIR METABOLITES [J].
CHEN, ZR ;
IRVINE, RJ ;
SOMOGYI, AA ;
BOCHNER, F .
LIFE SCIENCES, 1991, 48 (22) :2165-2171
[3]   Evaluation of 3′-azido-3′-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes:: Specificity and influence of the UGT2B7*2 polymorphism [J].
Court, MH ;
Krishnaswamy, S ;
Hao, Q ;
Duan, SX ;
Patten, CJ ;
Von Moltke, LL ;
Greenblatt, DJ .
DRUG METABOLISM AND DISPOSITION, 2003, 31 (09) :1125-1133
[4]   Adverse drug reactions to oxycodone and hydrocodone in CYP2D6 ultrarapid metabolizers [J].
de Leon, J ;
Dinsmore, L ;
Wedlund, P .
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, 2003, 23 (04) :420-421
[5]   DEFECTIVE N-OXIDATION OF SPARTEINE IN MAN - NEW PHARMACOGENETIC DEFECT [J].
EICHELBAUM, M ;
SPANNBRUCKER, N ;
STEINCKE, B ;
DENGLER, HJ .
EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1979, 16 (03) :183-187
[6]   Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data [J].
Gaedigk, A ;
Gotschall, RR ;
Forbes, NS ;
Simon, SD ;
Kearns, GL ;
Leeder, JS .
PHARMACOGENETICS, 1999, 9 (06) :669-682
[7]   Codeine intoxication associated with ultrarapid CYP2D6 metabolism [J].
Gasche, Y ;
Daali, Y ;
Fathi, M ;
Chiappe, A ;
Cottini, S ;
Dayer, P ;
Desmeules, J .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (27) :2827-2831
[8]   Polymorphisms in CYP2D6 duplication-negative individuals with the ultrarapid metabolizer phenotype:: a role for the CYP2D6*35 allele in ultrarapid metabolism? [J].
Lovlie, R ;
Daly, AK ;
Matre, GE ;
Molven, A ;
Steen, VM .
PHARMACOGENETICS, 2001, 11 (01) :45-55
[9]   POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN [J].
MAHGOUB, A ;
IDLE, JR ;
DRING, LG ;
LANCASTER, R ;
SMITH, RL .
LANCET, 1977, 2 (8038) :584-586
[10]   A frameshift mutation and alternate splicing in human brain generate a functional form of the pseudogene cytochrome P4502D7 that demethylates codeine to morphine [J].
Pai, HV ;
Kommaddi, RP ;
Chinta, SJ ;
Mori, T ;
Boyd, MR ;
Ravindranath, V .
JOURNAL OF BIOLOGICAL CHEMISTRY, 2004, 279 (26) :27383-27389