Annulation of imidazolines with bis-electrophiles: Synthesis of imidazo[1,2-a]pyridines

被引：48

作者：

Jones, RCF

Patel, P

Hirst, SC

Smallridge, MJ

机构：

[1] Open Univ, Dept Chem, Milton Keynes MK7 6AA, Bucks, England

[2] Univ Nottingham, Dept Chem, Nottingham NG7 2RD, England

来源：

TETRAHEDRON | 1998年 / 54卷 / 22期

关键词：

D O I：

10.1016/S0040-4020(98)00312-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1-Benzyl-2-(ethoxycarbonylmethylene)-2,3,4,5-tetrahydroimidazole undergoes annulation with a variety of 1,3-bis-electrophiles (alpha,beta-unsaturated acid derivatives, beta-ketoesters, se-unsaturated aldehydes) to form imidazo[1,2-a]pyridines. (C) 1998 Elsevier Science Ltd. All rights reserved.

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页码：6191 / 6200

页数：10

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