How hazardous are ionic liquids?: Structure-activity relationships and biological testing as important elements for sustainability evaluation

被引:309
作者
Jastorff, B
Störmann, R
Ranke, J
Mölter, K
Stock, F
Oberheitmann, B
Hoffmann, W
Hoffmann, J
Nüchter, M
Ondruschka, B
Filser, J
机构
[1] UFT Ctr Environm Res & Environm Technol, Dept Bioorgan Chem, D-28359 Bremen, Germany
[2] UFT Ctr Environm Res & Environm Technol, Dept Gen & Theoret Ecol, Bremen, Germany
[3] UFT Ctr Environm Res & Environm Technol, Dept Epidemiol, Bremen, Germany
[4] Ernst Moritz Arndt Univ Greifswald, Inst Community Med, D-17487 Greifswald, Germany
[5] Univ Jena, Inst Tech Chem & Environm Chem, D-07743 Jena, Germany
关键词
D O I
10.1039/b211971d
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
For ionic liquids only few toxicological and/or ecotoxicological data are available until now. A strategy is presented which aims at an environmental risk assessment of chemicals, using a combination of structure-activity relationships (SAR), toxicological and ecotoxicological tests and modelling. The parts "test-kit-concept" and "multidimensional risk analysis" are described in detail by means of selected imidazolium ionic liquids. The iterative process of this strategy offers a tool for sustainable product design.
引用
收藏
页码:136 / 142
页数:7
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