Diversity by design

被引:6
作者
Bradbury, A [1 ]
机构
[1] Int Sch Adv Studies, I-34012 Trieste, Italy
关键词
D O I
10.1016/S0167-7799(97)01142-6
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:99 / 102
页数:4
相关论文
共 11 条
[1]   Peptide agonist of the thrombopoietin receptor as potent as the natural cytokine [J].
Cwirla, SE ;
Balasubramanian, P ;
Duffin, DJ ;
Wagstrom, CR ;
Gates, CM ;
Singer, SC ;
Davis, AM ;
Tansik, RL ;
Mattheakis, LC ;
Boytos, CM ;
Schatz, PJ ;
Baccanari, DP ;
Wrighton, NC ;
Barrett, RW ;
Dower, WJ .
SCIENCE, 1997, 276 (5319) :1696-1699
[2]   In vitro selection and evolution of functional proteins by using ribosome display [J].
Hanes, J ;
Pluckthun, A .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (10) :4937-4942
[3]  
KAWASAKI G, 1991, Patent No. 05058
[4]   Functional mimicry of a protein hormone by a peptide agonist: The EPO receptor complex at 2.8 angstrom [J].
Livnah, O ;
Stura, EA ;
Johnson, DL ;
Middleton, SA ;
Mulcahy, LS ;
Wrighton, NC ;
Dower, WJ ;
Jolliffe, LK ;
Wilson, IA .
SCIENCE, 1996, 273 (5274) :464-471
[5]   Extending filamentous phage host range by the grafting of a heterologous receptor binding domain [J].
Marzari, R ;
Sblattero, D ;
Righi, M ;
Bradbury, A .
GENE, 1997, 185 (01) :27-33
[6]   Isolation of high-affinity monomeric human Anti-c-erbB-2 single chain Fv using affinity-driven selection [J].
Schier, R ;
Bye, J ;
Apell, G ;
McCall, A ;
Adams, GP ;
Malmqvist, M ;
Weiner, LM ;
Marks, JD .
JOURNAL OF MOLECULAR BIOLOGY, 1996, 255 (01) :28-43
[7]   Selectively infective phage (SIP) technology: A novel method for in vivo selection of interacting protein-ligand pairs [J].
Spada, S ;
Pluckthun, A .
NATURE MEDICINE, 1997, 3 (06) :694-696
[8]   PDZ domain of neuronal nitric oxide synthase recognizes novel C-terminal peptide sequences [J].
Stricker, NL ;
Christopherson, KS ;
Yi, BA ;
Schatz, PJ ;
Raab, RW ;
Dawes, G ;
Bassett, DE ;
Bredt, DS ;
Li, M .
NATURE BIOTECHNOLOGY, 1997, 15 (04) :336-342
[9]   Subtractive isolation of phage-displayed single-chain antibodies to thymic stromal cells by using intact thymic fragments [J].
VanEwijk, W ;
deKruif, J ;
Germeraad, WTV ;
Berendes, P ;
Ropke, C ;
Platenburg, PP ;
Logtenberg, T .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1997, 94 (08) :3903-3908
[10]   Human antibodies with sub-nanomolar affinities isolated from a large non-immunized phage display library [J].
Vaughan, TJ ;
Williams, AJ ;
Pritchard, K ;
Osbourn, JK ;
Pope, AR ;
Earnshaw, JC ;
McCafferty, J ;
Hodits, RA ;
Wilton, J ;
Johnson, KS .
NATURE BIOTECHNOLOGY, 1996, 14 (03) :309-314