DNA marker C04107 for copper toxicosis in a population of Bedlington terriers in the United Kingdom

被引：29

作者：

Holmes, NG

Herrtage, ME

Ryder, EJ

Binns, MM

机构：

[1] Anim Hlth Trust, Ctr Prevent Med, Newmarket CB8 7DW, Suffolk, England

[2] Univ Cambridge, Dept Clin Vet Med, Cambridge CB3 0ES, England

来源：

VETERINARY RECORD | 1998年 / 142卷 / 14期

关键词：

D O I：

10.1136/vr.142.14.351

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

The DNA microsatellite marker C04107, linked to the Bedlington terrier copper toxicosis locus, is used diagnostically in the USA to detect the disease allele, This marker has been typed in Bedlington terriers of known disease status in the United Kingdom, and it is concluded that it should be useful-in eradicating the disease from the breed in the UK. The marker also identified a dog which had been diagnosed on the basis of a liver biopsy as having the disease, as being unaffected; a second liver biopsy confirmed that the dog did not have copper toxicosis.

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收藏

页码：351 / 352

页数：2

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