First asymmetric synthesis of chiral 1,4-benzodioxane lignans

被引：40

作者：

Gu, WX

Jing, XB

Pan, XF ^{[1
]}

Chan, ASC

Yang, TK

机构：

[1] Lanzhou Univ, Dept Chem, Natl Lab Appl Organ Chem, Lanzhou 730000, Peoples R China

[2] Hong Kong Polytech Univ, Dept Appl Biol & Chem Technol, Hong Kong, Hong Kong, Peoples R China

[3] Natl Chung Hsing Univ, Dept Chem, Taichung 40227, Taiwan

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 32期

基金：

中国国家自然科学基金;

关键词：

asymmetric synthesis; 1,4-benzodioxane; lignans; neolignan;

D O I：

10.1016/S0040-4039(00)00820-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An asymmetric and regioselective total synthesis approach to 1,4-benzodioxane lignans was reported in which (2R,3R)- and (2S,3S)-3-(4-hydroxy-3-methoxyyhenyl)-2-hydroxymethyl-1,4-benzodioxan-6-carbaldehyde were synthesized firstly. A natural 1,4-benzodioxane neolignan was synthesized firstly by the synthesis approach. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：6079 / 6082

页数：4

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