Endothelial dysfunction and inflammation after percutaneous coronary intervention

被引：45

作者：

Blum, A

Schneider, DJ

Sobel, BE

Dauerman, HL

机构：

[1] Univ Vermont, Div Cardiol, Burlington, VT 05401 USA

[2] Poria Med Ctr, Dept Internal Med A, Lower Galilee, Israel

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 2004年 / 94卷 / 11期

关键词：

D O I：

10.1016/j.amjcard.2004.07.146

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We studied 30 consecutive patients who underwent coronary stenting with respect to postprocedure endothelial dysfunction and levels of pre- and postprocedure cytokines. Patients with severe impairment of flow-mediated dependent dilation, but not flow- mediated independent dilation, had higher concentrations of C-reactive protein before percutaneous coronary intervention (12.9 +/- 20.2 vs 5.6 +/- 13.0 mug/ml, p = 0.04) and 24 hours after stenting (18.8 +/- 20.8 vs 11.8 +/- 20.0 mug/ml, p = 0.05) than patients without severe abnormities of systemic endothelial function. Thus, enclothelium-clepenclent dilation abnormalities were related to the systemic inflammatory state, whereas enclothelium-inclepenclent dilation abnormalities were not related to the inflammatory status of the patient. (C) 2004 by Excerpto Medica Inc.

引用

收藏

页码：1420 / 1423

页数：4

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