Role of exercise in the assessment and management of neuromuscular disease in children

In the child with a neuromuscular disease (NMD), one can use exercise for the assessment of physiological function and as a therapeutic modality. Functions most relevant for assessment are muscle strength, muscle endurance, peak mechanical power, and O-2 cost of movement. Maximal aerobic power is less important because it seldom is the limiting factor in the child's ability to perform daily physical activities. There are very few well-designed controlled training interventions in children with NMD. There is, however, some evidence to suggest that maximal aerobic power, muscle strength, and O-2 cost of locomotion are trainable in children with NMD.