Switchable Wettability of Thermo-Responsive Biocompatible Nanofibrous Films Created by Electrospinning

被引：66

作者：

Gu, Shu-Ying ^{[1
,2
]}

Wang, Zhi-Mei ^{[1
]}

Li, Jian-Bo ^{[1
]}

Ren, Jie ^{[1
,2
]}

机构：

[1] Tongji Univ, Sch Mat Sci & Engn, Shanghai 200092, Peoples R China

[2] Tongji Univ, Sch Mat Sci & Engn, Minist Educ, Key Lab Adv Civil Engn Mat, Shanghai 200092, Peoples R China

来源：

MACROMOLECULAR MATERIALS AND ENGINEERING | 2010年 / 295卷 / 01期

关键词：

biocompatibility; electrospinning; films; switchable wettability; thermo-responsive; SUPERHYDROPHOBIC SURFACE; POLYMER BRUSHES; PH; POLY(N-ISOPROPYLACRYLAMIDE); NANOPARTICLES; FABRICATION; FIBERS; LAYER;

D O I：

10.1002/mame.200900215

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Thermo-responsive PNIPAAm/PLLA nanofibrous films with tunable surface morphologies and better biocompatibility were prepared by electrospinning technique. The electrospun composite films possessed a "bead-on-string" structure. The wettability of nanofibrous films was observed by water CA measurements. The results showed that the electrospinning process and addition of PLLA did not change the thermosensitivity of PNIPAAm. The wettability of electrospun PNIPAAm/PLLA composite films could switch from superhydrophilic to superhydrophobic when the temperature increased from 20 to 50 degrees C. Electrospinning is a promising way to create stimuli-responsive surfaces with potential application in the design and tactics of controllable drug delivery system.

引用

页码：32 / 36

页数：5

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