A perspective on male osteoporosis

被引:21
作者
Binkley, Neil [1 ,2 ]
机构
[1] Univ Wisconsin, Osteoporosis Clin Ctr, Madison, WI USA
[2] Univ Wisconsin, Inst Aging, Madison, WI USA
来源
BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY | 2009年 / 23卷 / 06期
关键词
osteoporosis; fragility fracture; men; dual-energy X-ray absorptiometry; sarcopenia; BONE-MINERAL DENSITY; ANDROGEN DEPRIVATION THERAPY; ISCD OFFICIAL POSITIONS; VITAMIN-D DEFICIENCY; OLDER MEN; HIP FRACTURE; RISK-FACTORS; ELDERLY-MEN; REPLACEMENT THERAPY; VERTEBRAL FRACTURES;
D O I
10.1016/j.berh.2009.10.001
中图分类号
R5 [内科学];
学科分类号
100201 [内科学];
摘要
Osteoporosis and fragility fracture become common with advancing age in men. The incidence of osteoporosis-related fracture is similar to myocardial infarction and exceeds that of lung and prostate carcinoma combined. These fractures cause Substantial morbidity, and the mortality following hip fracture is greater in men than in women. A decline in sex steroids and glucocorticoid and alcohol use, among other factors, contribute to bone loss and fracture risk. Approaches to reduce fracture risk in men are very similar to that in women - recognising and addressing muscle weakness/falls risk and optimising nutrition, with emphasis on calcium and vitamin D and medications when appropriate. Despite the high prevalence, osteoporosis remains largely undiagnosed and undertreated. Hopefully, increased recognition of male osteoporosis by health-care providers and the men themselves, in combination with recent consensus recommendations for treatment based on fracture-risk estimation, will reduce the burden of fragility fracture in men. (C) 2009 Published by Elsevier Ltd.
引用
收藏
页码:755 / 768
页数:14
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