Total synthesis of (±)-rhazinal, an alkaloidal spindle toxin from Kopsia teoi

被引：69

作者：

Banwell, MG ^{[1
]}

Edwards, AJ

Jolliffe, KA

Smith, JA

Hamel, E

Verdier-Pinard, P

机构：

[1] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 0200, Australia

[2] Univ Sydney, Sch Chem, Sydney, NSW 2006, Australia

[3] NCI, Div Canc Treatment & Diagnosis, NIH, Screening Technol Branch,Dev Therapeut Program, Frederick, MD 21702 USA

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 02期

关键词：

D O I：

10.1039/b209992f

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The title alkaloid I and its B-nor-congener 3, both of which display potent and unusual anti-mitotic properties, have been synthesized in racemic form and characterised by single-crystal X-ray analysis.

引用

页码：296 / 305

页数：10

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