The role of physical proximity in nosocomial diarrhea

被引：79

作者：

Chang, VT

Nelson, K

机构：

[1] Univ Med & Dent New Jersey, New Jersey Med Sch, Sect Hematol Oncol 111,Dept Med, Vet Affairs New Jersey Hlth Care Syst E Orange, E Orange, NJ 07019 USA

[2] Good Samaritan Hosp, Dept Med, Baltimore, MD USA

[3] Johns Hopkins Med Inst, Sch Hyg & Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA

来源：

CLINICAL INFECTIOUS DISEASES | 2000年 / 31卷 / 03期

关键词：

D O I：

10.1086/314030

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To examine physical proximity as a risk factor for the nosocomial acquisition of Clostridium difficile-associated diarrhea (CDAD) and of antibiotic-associated diarrhea (AAD), we assessed a retrospective cohort of 2859 patients admitted to a community hospital from 1 March 1987 through 31 August 1987. Of these patients, 68 had nosocomial CDAD and 54 had nosocomial AAD, In multivariate analysis, physical proximity to a patient with CDAD (relative risk [RR], 1.86; 95% confidence interval [CI], 1.06-3.28), exposure to clindamycin (RR, 4.22; 95% CI, 2.11-8.45), and the number of antibiotics taken (RR, 1.49; 95% CI, 1.23-1.81) were significant. For patients with nosocomial AAD, exposure to a roommate with AAD (RR, 3.94; 95% CI, 1.27-12.24), a stay in an intensive care unit or cardiac care unit(RR, 1.93; 95% CI, 1.05-3.53), and the number of antibiotics taken OCR, 2.01; 95% CI, 1.67-2.40) were significant risk factors. Physical proximity may be an independent risk factor for acquisition of nosocomial CDAD and AAD,

引用

页码：717 / 722

页数：6

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