Molecular analysis of duck hepatitis virus type 1

被引：189

作者：

Ding, Chunyu ^{[1
]}

Zhang, Dabing ^{[1
]}

机构：

[1] China Agr Univ, Key Lab Prevent Vet Med, Minist Agr, Coll Vet Med, Beijing 100094, Peoples R China

来源：

VIROLOGY | 2007年 / 361卷 / 01期

关键词：

picomavirus; duck hepatitis virus 1; genome; AIG1; domain;

D O I：

10.1016/j.virol.2007.01.007

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The genome sequence of a duck hepatitis virus type 1 (DHV-1) strain was determined. Comparative sequence analysis showed that the genome possesses a typical picornarivus organization and also exhibits several unique features, such as the similarity of internal ribosome entry site to that of Porcine teschovirus 1 and Hepatitis C virus, the presence of a longest 3' untranslated region and a shorter leader protein in the Picornaviridae, the absence of a predicted maturation cleavage of VP0, the association of an aphthovirus-like 2A1 and parechovirus-like 2A2, and the unprecedented presence of an AIG1 domain in the N-terminus of 2A2. It is concluded that DHV-1 belongs to a new group of the family Picornaviridae that may form a separate genus most closely related to the genus Parechovirus. (c) 2007 Elsevier Inc. All rights reserved.

引用

页码：9 / 17

页数：9

共 22 条

[1] Functional analyses of RNA structures shared between the internal ribosome entry sites of hepatitis C virus and the picornavirus porcine teschovirus 1 Talfan [J].