Cardiovascular disease in diabetes mellitus type 2: a potential role for novel cardiovascular risk factors

被引:92
作者
Hayden, JM [1 ]
Reaven, PD [1 ]
机构
[1] Carl T Hayden VAMC, Dept med CS 111E, Phoenix, AZ 85012 USA
关键词
D O I
10.1097/00041433-200010000-00010
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A major consequence of diabetes mellitus type 2 is the accelerated development of atherosclerosis, Assessment of conventional risk factors such as plasma lipids, lipoproteins and hypertension only partly account for the excessive risk of developing cardiovascular disease in this population. Increasing evidence has emerged suggesting that conditions associated with diabetes mellitus type 2, such as insulin resistance, hyperinsulinemia and hyperglycemia, may also play a significant role in regulating 'novel' cardiovascular risk factors. These factors and their potential roles in the development of atherosclerosis and cardiovascular events are discussed in this review. Curr Opin Lipidol 11:519-528 (C) 2000 Lippincott Williams & Wilkins.
引用
收藏
页码:519 / 528
页数:10
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