Palladium-catalyzed hydrostannylations of highly hindered acetylenes in hexane

被引：25

作者：

Semmelhack, MF ^{[1
]}

Hooley, RJ ^{[1
]}

机构：

[1] Princeton Univ, Dept Chem, Princeton, NJ 08540 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 30期

关键词：

D O I：

10.1016/S0040-4039(03)01327-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Hexane is particularly favorable as a solvent for hydrostannylation of hindered internal alkynes by minimizing the competing formation of H-2 and Bu3SnSnBu3. The optimum conditions involve Pd(OAc), and a donor monophosphine (PCy3) in hexane at 23degreesC. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：5737 / 5739

页数：3

共 8 条

[1] Radical hydrostannylation, Pd(0)-catalyzed hydrostannylation, stannylcupration of propargyl alcohols and enynols: Regio- and stereoselectivities [J].