Drug eluting stents: are human and animal studies comparable?

被引：238

作者：

Virmani, R

Kolodgie, FD

Farb, A

Lafont, A

机构：

[1] Armed Forces Inst Pathol, Dept Cardiovasc Pathol, Washington, DC 20306 USA

[2] Univ Paris 05, Hop Europeen Georges Pompidou, INSERM E00 16, Paris, France

来源：

HEART | 2003年 / 89卷 / 02期

关键词：

D O I：

10.1136/heart.89.2.133

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Animal models of stenting probably predict human responses as the stages of healing are remarkably similar. What is characteristically different is the temporal response to healing, which is substantially prolonged in humans. The prevention of restenosis in recent clinical trials of drug eluting stents may represent a near absent or incomplete phase of intimal healing. Continued long term follow up of patients with drug eluting stents for major adverse cardiac events and angiographic restenosis is therefore imperative.

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收藏

页码：133 / 138

页数：6

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