A 12-year-old girl with antimitochondrial antibody-positive autoimmune hepatitis

被引：28

作者：

Gregorio, GV

Portmann, B

Mowat, AP

Vergani, D

MieliVergani, G

机构：

[1] UNIV LONDON KINGS COLL, SCH MED & DENT, DEPT CHILD HLTH, LONDON SE5 9PJ, ENGLAND

[2] UNIV LONDON KINGS COLL, SCH MED & DENT, INST LIVER STUDIES, LONDON SE5 9PJ, ENGLAND

[3] UCL, SCH MED, INST HEPATOL, LONDON W1N 8AA, ENGLAND

来源：

JOURNAL OF HEPATOLOGY | 1997年 / 27卷 / 04期

关键词：

antimitochondrial antibody; autoimmune hepatitis; childhood; pyruvate dehydrogenase;

D O I：

10.1016/S0168-8278(97)80093-1

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Autoimmune hepatitis is rare and, in childhood, is typically associated with either the nuclear and/or smooth muscle antibody or with the liver kidney microsomal type 1 antibody, Antimitochondrial antibodies, which are considered diagnostic of primary biliary cirrhosis, have not been described in the paediatric age, We report for the first time a 12-year-old girl with antimitochondrial-antibody-positive autoimmune hepatitis. Antimitochondrial antibody positivity was determined by immunofluorescence and immunoblot, The patient's age, clinical, biochemical and histological features and response to immunosuppressive treatment support the diagnosis of autoimmune hepatitis.

引用

页码：751 / 754

页数：4

共 12 条

[1] ANTIBODIES TO SOLUBLE LIVER ANTIGEN, P450IID6, AND MITOCHONDRIAL COMPLEXES IN CHRONIC HEPATITIS [J].