Characterizing exhaled airflow from breathing and talking

被引:428
作者
Gupta, Jitendra K. [1 ]
Lin, Chao-Hsin [2 ]
Chen, Qingyan [1 ]
机构
[1] Purdue Univ, Sch Mech Engn, Natl Air Transportat Ctr Excellence Res Intermoda, W Lafayette, IN 47906 USA
[2] Boeing Commercial Airplanes, Environm Control Syst, Everett, WA USA
关键词
Source model; Airborne infection; Airflow; Visualization; Opening area; TRANSPORT CHARACTERISTICS; TUBERCULOSIS; PARTICLES; DROPLETS; BURDEN; VALUES;
D O I
10.1111/j.1600-0668.2009.00623.x
中图分类号
TU [建筑科学];
学科分类号
0813 ;
摘要
P>The exhaled air of infected humans is one of the prime sources of contagious viruses. The exhaled air comes from respiratory events such as the coughing, sneezing, breathing and talking. Accurate information on the thermo-fluid characteristics of the exhaled airflow can be important for prediction of infectious disease transmission. The present study developed a source model to provide the thermo-fluid conditions of the exhaled air from the breathing and talking processes. The source model is a set of equations obtained from the measurements of the flow rate, flow direction, and area of mouth/nose opening with human subjects. It was found that the exhaled flow rate over time can be represented as a sinusoidal function for breathing and a constant for talking. The flow rates can be calculated by physiological parameters of a subject. The direction of the exhalation jet did not vary much between subjects and the area of mouth/nose opening could be regarded as a constant. Though the mouth/nose opening size varied among subjects, they were not correlated with the physiological parameters of the subjects. If combined with appropriate virus and droplet distribution information, the model can be used to describe the disease source due to breathing and talking. Practical Implications Accurate prediction of airborne disease transmission, and the infection prone zones, can aid in identifying and implementing the control strategies. With the recent advancements, Computational Fluid Dynamics (CFD) has become a powerful tool in predicting the disease transmission. Accurate prediction of the transmission by these CFD simulations requires information on sources and sinks of infectious viruses and models for dispersion of these viruses. The exhaled air of an infected human is one of the prime sources of disease viruses. In the present study, measurements of the flow were conducted on human subjects to develop models for the flow boundary conditions for the exhalation and inhalation during breathing and talking.
引用
收藏
页码:31 / 39
页数:9
相关论文
共 28 条
[1]  
Altman P. L., 1971, RESPIRATION CIRCULAT
[2]  
Araujo Paula Beatriz, 2004, Rev. Bras. Zool., V21, P1, DOI 10.1590/S0101-81752004000100001
[3]  
BALDWIN ED, 1948, MEDICINE, V27, P243
[4]   Characterization of expiration air jets and droplet size distributions immediately at the mouth opening [J].
Chao, C. Y. H. ;
Wan, M. P. ;
Morawska, L. ;
Johnson, G. R. ;
Ristovski, Z. D. ;
Hargreaves, M. ;
Mengersen, K. ;
Corbett, S. ;
Li, Y. ;
Xie, X. ;
Katoshevski, D. .
JOURNAL OF AEROSOL SCIENCE, 2009, 40 (02) :122-133
[5]   The growing burden of tuberculosis - Global trends and interactions with the HIV epidemic [J].
Corbett, EL ;
Watt, CJ ;
Walker, N ;
Maher, D ;
Williams, BG ;
Raviglione, MC ;
Dye, C .
ARCHIVES OF INTERNAL MEDICINE, 2003, 163 (09) :1009-1021
[6]   EFFECT OF BREATHING ROUTE ON VENTILATION AND VENTILATORY DRIVE [J].
DOUGLAS, NJ ;
WHITE, DP ;
WEIL, JV ;
ZWILLICH, CW .
RESPIRATION PHYSIOLOGY, 1983, 51 (02) :209-218
[7]  
DUGUID JP, 1945, J HYGIENE, V54, P471
[8]   Global burden of tuberculosis - Estimated incidence, prevalence, and mortality by country [J].
Dye, C ;
Scheele, S ;
Dolin, P ;
Pathania, V ;
Raviglione, RC .
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (07) :677-686
[9]   Inhaling to mitigate exhaled bioaerosols [J].
Edwards, DA ;
Man, JC ;
Brand, P ;
Katstra, JP ;
Sommerer, K ;
Stone, HA ;
Nardell, E ;
Scheuch, G .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2004, 101 (50) :17383-17388
[10]   Influenza Virus in Human Exhaled Breath: An Observational Study [J].
Fabian, Patricia ;
McDevitt, James J. ;
DeHaan, Wesley H. ;
Fung, Rita O. P. ;
Cowling, Benjamin J. ;
Chan, Kwok Hung ;
Leung, Gabriel M. ;
Milton, Donald K. .
PLOS ONE, 2008, 3 (07)