Synthesis of resveratrol using a direct decarbonylative Heck approach from resorcylic acid

被引：93

作者：

Andrus, MB ^{[1
]}

Liu, J ^{[1
]}

Meredith, EL ^{[1
]}

Nartey, E ^{[1
]}

机构：

[1] Brigham Young Univ, Dept Chem & Biochem, Provo, UT 84602 USA

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 26期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/S0040-4039(03)01131-6

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The phytoalexin resveratrol has been made using a decarbonylative Heck reaction. The acid chloride derived from 3.5-dihydroxybenzoic acid was coupled with 4-acetoxystyrene in the presence of palladium acetate and N,N-bis-(2,6-diisopropylphenyl)dihvdroimidazolium chloride to give the substituted stilbene in 73%, yield as the key step. (C) 2003 Published by Elsevier Science Ltd.

引用

页码：4819 / 4822

页数：4

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