Workshop studies with monoclonal antibodies identifying a novel porcine differentiation antigen, SWC9

被引:20
作者
Dominguez, J [1 ]
Ezquerra, A
Alonso, F
Bullido, R
McCullough, K
Summerfield, A
Bianchi, A
Zwart, RJ
Kim, YB
Blecha, F
Eicher, S
Murtaugh, MP
Pampusch, M
Burger, K
机构
[1] INIA, Ctr Invest Sanidad Anim, Madrid 28130, Spain
[2] Inst Virol & Immunoprophylaxis, CH-3147 Mittelhausern, Switzerland
[3] DLO, Cent Vet Inst, ID, NL-8200 AB Lelystad, Netherlands
[4] Finch Univ Hlth Sci Chicago Med Sch, Dept Microbiol & Immunol, N Chicago, IL 60064 USA
[5] Kansas State Univ, Dept Anat & Physiol, Manhattan, KS 66506 USA
[6] Univ Minnesota, Dept Vet Pathobiol, St Paul, MN 55108 USA
关键词
monoclonal antibody; macrophage; differentiation antigen;
D O I
10.1016/S0165-2427(97)00110-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Two monoclonal antibodies (mAb) within cluster M4 of the myeloid section of the Second International Swine CD Workshop, C4 (No. 144) and PM18-7 (No, 192), showed reactivity with thymocytes and among cells of myelomonocytic origin with mature macrophages but not with monocytes and granulocytes. Both mAb recognize a protein showing two bands of 205 kDa and 130 kDa under both reducing and non-reducing conditions. Although epitope mapping with these mAb could not be performed, this cluster received the SWC9 designation. (C) 1998 Elsevier Science B.V.
引用
收藏
页码:343 / 349
页数:7
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