Noncovalent Assembly of TEMPO Radicals Pair-wise Embedded on a DNA Duplex

被引：11

作者：

Atsumi, Hiroshi ^{[1
]}

Maekawa, Kensuke ^{[1
]}

Nakazawa, Shigeaki ^{[2
,3
]}

Shiomi, Daisuke ^{[2
,3
]}

Sato, Kazunobu ^{[2
,3
]}

Kitagawa, Masahiro ^{[4
]}

Takui, Takeji ^{[2
,3
]}

Nakatani, Kazuhiko ^{[1
]}

机构：

[1] Osaka Univ, Dept Regulatory Bioorgan Chem, ISIR, Ibaraki 5670047, Japan

[2] Osaka City Univ, Grad Sch Sci, Dept Chem, Sumiyoshi Ku, Osaka 5588585, Japan

[3] Osaka City Univ, Grad Sch Sci, Dept Mat Sci, Sumiyoshi Ku, Osaka 5588585, Japan

[4] Osaka Univ, Dept Syst Innovat, Grad Sch Engn Sci, Toyonaka, Osaka 5608531, Japan

来源：

CHEMISTRY LETTERS | 2010年 / 39卷 / 06期

关键词：

BINDING; EPR;

D O I：

10.1246/cl.2010.556

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

We have synthesized and characterized a new G G mismatch binding ligand containing a TEMPO radical. The two mismatch binding ligands cooperatively bound to the CGG/CGG triad and an apparent binding constant was in the order of 10(5)M(-1). The tumbling of the ligand on a DNA duplex was ten times slower than that of the unbound ligand. Asymmetric addressability of two TEMPO radicals on DNA is shown.

引用

页码：556 / 557

页数：2

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