Inhibition of HIV-1 protease by water-soluble lignin-like substance from an edible mushroom, Fuscoporia obliqua

被引：52

作者：

Ichimura, T

Watanabe, O

Maruyama, S

机构：

[1] Agcy Ind Sci & Technol, Natl Inst Biosci & Human Technol, Tsukuba, Ibaraki 305, Japan

[2] Hokkaido Food Proc Res Ctr, Ebetsu, Hokkaido 069, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1998年 / 62卷 / 03期

关键词：

HIV-1; protease; lignin; mushroom;

D O I：

10.1271/bbb.62.575

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Activity that inhibited protease of human immunodeficiency virus type 1 was found in boiling water extracts of an edible mushroom, Fuscoporia obliqua. The active component was identified as a water-soluble lignin derivative of high molecular weight. Other polyphenols of low molecular weight and monomeric components of lignin did not inhibit the protease.

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收藏

页码：575 / 577

页数：3

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