Functional Status in Left Ventricular Assist Device-Supported Patients: A Literature Review

被引：37

作者：

Abshire, Martha ^{[1
]}

Himmelfarb, Cheryl R. Dennison ^{[1
,2
]}

Russell, Stuart D. ^{[2
]}

机构：

[1] Johns Hopkins Univ, Sch Nursing, Baltimore, MD USA

[2] Johns Hopkins Univ, Sch Med, Baltimore, MD USA

来源：

JOURNAL OF CARDIAC FAILURE | 2014年 / 20卷 / 12期

基金：

美国国家卫生研究院;

关键词：

Heart-assist device; functional status; quality of life; outcomes; left ventricular assist device; QUALITY-OF-LIFE; HEART-FAILURE PATIENTS; INCREASING PUMP SPEED; EXERCISE CAPACITY; FLOW; IMPLANTATION; OUTCOMES; MANAGEMENT; REHABILITATION; STRATEGIES;

D O I：

10.1016/j.cardfail.2014.08.011

中图分类号：

R5 [内科学];

学科分类号：

100201 [内科学];

摘要：

The prevalence of advanced heart failure (HF) is increasing because of the aging population and improvements in HF management strategies. Left ventricular assist device (LVAD) technology and management continue to advance rapidly, and it is anticipated that the number of LVAD implants will increase. LVADs have been demonstrated to extend life and improve outcomes in patients with advanced HF. The purpose of this article is to review and synthesize the evidence on impact of LVAD therapy on functional status. Significant functional gains were demonstrated in patients supported by LVAD throughout the 1st year, with most improvement in distance walked and peak oxygen consumption demonstrated in the 1st 6 months. Interventions to enhance exercise performance have had inconsistent effects on functional status. Poor exercise performance was associated with increased risk of adverse events. Functional status improved with LVAD therapy, although performance remained substantially reduced compared with age-adjusted norms. There is tremendous need to enhance our understanding of factors influencing functional outcomes in this high-risk population.

引用

页码：973 / 983

页数：11

共 49 条

[1]

Clinical Strategies and Outcomes in Advanced Heart Failure Patients Older Than 70 Years of Age Receiving the HeartMate II Left Ventricular Assist Device A Community Hospital Experience [J].