Behavioral and neuroeconomics of drug addiction: Competing neural systems and temporal discounting processes

被引：372

作者：

Bickel, Warren K.

Miller, Michelle L.

Yi, Richard

Kowal, Benjamin P.

Lindquist, Diana M.

Pitcock, Jeffery A.

机构：

[1] Univ Arkansas Med Sci, Coll Med, Fred & Louise Dierks Res Labs, Inst Psychiat Res,Addict Res Ctr,Dept Psychiat, Little Rock, AR 72205 USA

[2] Univ Arkansas Med Sci, Coll Med, Fred & Louise Dierks Res Labs, Inst Psychiat Res,Addict Res Ctr,Dept Radiol, Little Rock, AR 72205 USA

[3] Univ Cincinnati, Cincinnati, OH USA

来源：

DRUG AND ALCOHOL DEPENDENCE | 2007年 / 90卷

关键词：

behavioral economics; neuroeconomics; temporal discounting; functional magnetic resonance imaging (fMRI); addiction; decision making;

D O I：

10.1016/j.drugalcdep.2006.09.016

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

We review behavioral- and neuroeconomic research that identifies temporal discounting as an important component in the development and maintenance of drug addiction. First, we review behavioral economic research that explains and documents the contribution of temporal discounting to addiction. This is followed with recent insights from neuroeconomics that may provide an explanation of why drug-dependent individuals discount the future. Specifically. neuroeconomics has identified two competing neural systems that are related to temporal discounting using brain-imaging techniques that examine the relative activation of different brain regions for temporal discounting. According to the competing neural systems account, choices for delayed outcomes are related to the prefrontal cortex (i.e., the "executive system") and choices for immediate outcomes are related to the limbic brain regions (i.e., the "impulsive system"). Temporal discounting provides a useful framework for future imaging research, and suggests a novel approach to designing effective drug dependence prevention and treatment programs. (c) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：S85 / S91

页数：7

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