Cathepsin-6, a novel cysteine proteinase showing homology with and co-localized expression with cathepsin J/P in the labyrinthine layer of mouse placenta

被引：17

作者：

Nakajima, A ^{[1
]}

Kataoka, K ^{[1
]}

Takata, Y ^{[1
]}

Huh, NH ^{[1
]}

机构：

[1] Toyama Med & Pharmaceut Univ, Fac Med, Dept Biochem, Toyama 9300194, Japan

来源：

BIOCHEMICAL JOURNAL | 2000年 / 349卷

关键词：

development; differential display; in situ hybridization; trophoblast;

D O I：

10.1042/bj3490689

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel cysteine proteinase, cathepsin-6, was isolated by RNA differential display from mouse placenta. Cathepsin-6 showed the highest homology with cathepsin J (same as P) and L. The structural features including the catalytic triad of the C1 proteinase family were well conserved in cathepsin-6. The expression of cathepsin-6 and cathepsin J/P was restricted in labyrinthine trophoblasts of the placenta.

引用

页码：689 / 692

页数：4

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