Early investigation and treatment of obstructive sleep apnoea after acute stroke

被引:65
作者
Broadley, Simon A.
Jorgensen, Lisbeth
Cheek, Alison
Salonikis, Suzie
Taylor, Jamie
Thompson, Philip D.
Antic, Ral
机构
[1] Royal Adelaide Hosp, Dept Neurol, Adelaide, SA 5000, Australia
[2] Univ Adelaide, Dept Med, Adelaide, SA 5005, Australia
[3] Royal Adelaide Hosp, Dept Thorac Med, Adelaide, SA 5000, Australia
[4] Royal Adelaide Hosp, Speech Pathol Dept, Adelaide, SA 5000, Australia
[5] Royal Adelaide Hosp, Dept Radiol, Adelaide, SA 5000, Australia
关键词
acute stroke; obstructive sleep apnoea; hypertension; prevalence; epidemiology; obesity;
D O I
10.1016/j.jocn.2006.01.017
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Obstructive sleep apnoea (OSA) is an independent risk factor for hypertension, which is a major cause of stroke. The prevalence and associations of OSA in a cohort of stroke patients were studied. The safety and tolerability of early treatment with nasal continuous airways pressure (nCPAP) was also assessed. Consecutive subjects admitted with acute stroke were assessed clinically, radiologically and with scales assessing prior OSA risk, dysphagia and disability. Sleep studies were performed within the first few days of admission using a portable diagnostic system. Twenty-nine of 55 (53%) subjects had evidence of OSA, using an apnoea-hypopnoea index (AHI) of 10 or greater. The AHI was significantly associated with an index of prior OSA symptoms, but not with history of hypertension, degree of dysphagia, or type and severity of stroke. Use of a portable diagnostic system for detecting OSA in the acute stroke setting was well tolerated. OSA is common after acute stroke and exceeds rates seen in control populations of similar age (53% vs. 11%). Early treatment with nCPAP was effective and well tolerated. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:328 / 333
页数:6
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