WRKY transcription factors

被引:2280
作者
Rushton, Paul J. [2 ]
Somssich, Imre E. [3 ]
Ringler, Patricia [1 ]
Shen, Qingxi J. [1 ]
机构
[1] Univ Nevada, Sch Life Sci, Las Vegas, NV 89154 USA
[2] S Dakota State Univ, Dept Biol & Microbiol, Brookings, SD 57007 USA
[3] Max Planck Inst Pflanzenzuchtungsforsch, Abt Mol Phytopathol, D-50829 Cologne, Germany
基金
美国食品与农业研究所;
关键词
DNA-BINDING PROTEINS; ARABIDOPSIS-THALIANA; DISEASE-RESISTANCE; LEAF SENESCENCE; GENE-EXPRESSION; DEFENSE RESPONSES; PLANT SENESCENCE; FACTORS INTERACT; SALICYLIC-ACID; FACTOR FAMILY;
D O I
10.1016/j.tplants.2010.02.006
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
WRKY transcription factors are one of the largest families of transcriptional regulators in plants and form integral parts of signalling webs that modulate many plant processes. Here, we review recent significant progress in WRKY transcription factor research. New findings illustrate that WRKY proteins often act as repressors as well as activators, and that members of the family play roles in both the repression and derepression of important plant processes. Furthermore, it is becoming clear that a single WRKY transcription factor might be involved in regulating several seemingly disparate processes. Mechanisms of signalling and transcriptional regulation are being dissected, uncovering WRKY protein functions via interactions with a diverse array of protein partners, including MAP kinases, MAP kinase kinases, 14-3-3 proteins, calmodulin, histone deacetylases, resistance proteins and other WRKY transcription factors. WRKY genes exhibit extensive autoregulation and cross-regulation that facilitates transcriptional reprogramming in a dynamic web with built-in redundancy.
引用
收藏
页码:247 / 258
页数:12
相关论文
共 98 条
[1]   Isolation of two somatic embryogenesis-related genes from orchardgrass (Dactylis glomerata) [J].
Alexandrova, KS ;
Conger, BV .
PLANT SCIENCE, 2002, 162 (02) :301-307
[2]   Epigenetic control of a transcription factor at the cross section of two antagonistic pathways [J].
Alvarez-Venegas, Raul ;
Al Abdallat, Ayed ;
Guo, Ming ;
Alfano, James R. ;
Avramova, Zoya .
EPIGENETICS, 2007, 2 (02) :106-113
[3]   The MAP kinase substrate MKS1 is a regulator of plant defense responses [J].
Andreasson, E ;
Jenkins, T ;
Brodersen, P ;
Thorgrimsen, S ;
Petersen, NHT ;
Zhu, SJ ;
Qiu, JL ;
Micheelsen, P ;
Rocher, A ;
Petersen, M ;
Newman, MA ;
Nielsen, HB ;
Hirt, H ;
Somssich, I ;
Mattsson, O ;
Mundy, J .
EMBO JOURNAL, 2005, 24 (14) :2579-2589
[4]   MAP kinase signalling cascade in Arabidopsis innate immunity [J].
Asai, T ;
Tena, G ;
Plotnikova, J ;
Willmann, MR ;
Chiu, WL ;
Gomez-Gomez, L ;
Boller, T ;
Ausubel, FM ;
Sheen, J .
NATURE, 2002, 415 (6875) :977-983
[5]  
Ay N, 2009, PLANT J, V58, P333, DOI [10.1111/j.0960-7412.2009.03782.x, 10.1111/j.1365-313X.2008.03782.x]
[6]   The natural history of the WRKY-GCM1 zinc fingers and the relationship between transcription factors and transposons [J].
Babu, M. Madan ;
Iyer, Lakshminarayan M. ;
Balaji, S. ;
Aravind, L. .
NUCLEIC ACIDS RESEARCH, 2006, 34 (22) :6505-6520
[7]   MEME SUITE: tools for motif discovery and searching [J].
Bailey, Timothy L. ;
Boden, Mikael ;
Buske, Fabian A. ;
Frith, Martin ;
Grant, Charles E. ;
Clementi, Luca ;
Ren, Jingyuan ;
Li, Wilfred W. ;
Noble, William S. .
NUCLEIC ACIDS RESEARCH, 2009, 37 :W202-W208
[8]   Identification of novel pathogen-responsive cis-elements and their binding proteins in the promoter of OsWRKY13, a gene regulating rice disease resistance [J].
Cai, Meng ;
Qiu, Deyun ;
Yuan, Ting ;
Ding, Xinhua ;
Li, Hongjing ;
Duan, Liu ;
Xu, Caiguo ;
Li, Xianghua ;
Wang, Shiping .
PLANT CELL AND ENVIRONMENT, 2008, 31 (01) :86-96
[9]   Proteomic profiling of tandem affinity purified 14-3-3 protein complexes in Arabidopsis thaliana [J].
Chang, Ing-Feng ;
Curran, Amy ;
Woolsey, Rebekah ;
Quilici, David ;
Cushman, John C. ;
Mittler, Ron ;
Harmon, Alice ;
Harper, Jeffrey F. .
PROTEOMICS, 2009, 9 (11) :2967-2985
[10]   Studies on DNA-binding selectivity of WRKY transcription factors lend structural clues into WRKY-domain function [J].
Ciolkowski, Ingo ;
Wanke, Dierk ;
Birkenbihl, Rainer P. ;
Somssich, Imre E. .
PLANT MOLECULAR BIOLOGY, 2008, 68 (1-2) :81-92