Elderly heart failure patients with drug-induced serious hyperkalemia

被引：17

作者：

Vanpee, D ^{[1
]}

Swine, C ^{[1
]}

机构：

[1] Univ Catholique Louvain, Mont Godinne Univ Hosp, Dept Geriatr, B-5530 Yvoir, Belgium

来源：

AGING-CLINICAL AND EXPERIMENTAL RESEARCH | 2000年 / 12卷 / 04期

关键词：

angiotensin converting enzyme inhibitor (ACE); congestive heart failure; elderly; hyperkalemia; spironolactone;

D O I：

10.1007/BF03339853

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

We report four cases of hyperkalemia induced by the association of spironolactone with ACE inhibitor in geriatric patients. Over a period of one year, four elderly patients treated for congestive heart failure with this association were admitted to the Geriatric Ward with serious hyperkalemia. These occurrences represented one third of all-cause severe hyperkalemia cases admitted during this one-year period. A common observation in our cases was that the dose of spironolactone employed far exceeded the recommended dosages. These cases illustrate that spironolactone dosage must be kept low in the setting of chronic congestive heart failure treatment, as well as the need for close monitoring of frail elderly patients who are given this combination. (Aging Clin. Exp. Res. 12: 315-319, 2000) (C) 2000, Editrice Kurtis.

引用

页码：315 / 319

页数：5

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