Fur mutants of Pseudomonas aeruginosa PAO1:: phenotypic characterization in terms of iron-dependent pattern of deregulation of pyoverdin synthesis

被引：3

作者：

Johnová, A

Dobisová, M

Abdallah, MA

Kyslík, P

机构：

[1] Acad Sci Czech Republ, Inst Microbiol, Lab Enzyme Technol, CR-14220 Prague 4, Czech Republic

[2] Ecole Super Biotechnol Strasbourg, Dept Recepteurs & Prot Membrannaires, Lab Chim Microbienne, CNRS,UPR 9050, F-67400 Illkirch Graffenstaden, France

来源：

BIOTECHNOLOGY LETTERS | 2003年 / 25卷 / 03期

关键词：

Fur mutants; production deregulation; Pseudomonas aeruginosa; pyoverdin; specific growth rate;

D O I：

10.1023/A:1022329321369

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Fur mutants (Mn-r) of Pseudomonas aeruginosa Fe10 (FF13 and FF28) and PAO1 (FPA12) were evaluated for the pattern of deregulation of pyoverdin synthesis in iron-replete medium with Casamino acids [CAM( Fe)] or succinate [SM(Fe)]. With respect to siderophore synthesis, we found in CAM( Fe) medium two Fur phenotypes: FurA (full deregulation, FF13) and FurB (partial deregulation, FF28 and FPA12). Fur mutants compared to parental strains grew with slower specific growth rates on SM(0) and CAM(0) media in a stirred bioreactor. Fur mutants grew in SM(0) with mu about half of that in CAM(0).

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页码：235 / 239

页数：5

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