Carbohydrate-based combinatorial libraries

被引：58

作者：

Sofia, MJ ^{[1
]}

机构：

[1] Transcell Technol Inc, Cranbury, NJ 08512 USA

来源：

MOLECULAR DIVERSITY | 1998年 / 3卷 / 02期

关键词：

carbohydrates; combinatorial; glycoconjugates; libraries; solid phase; solution phase;

D O I：

10.1023/A:1009650424835

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Carbohydrate-based combinatorial libraries are tremendously valuable for studying the role of sugars in biology and for expanding accessible molecular diversity needed in broad-based drug screening programs. This review discusses the issues that are relevant to the successful implementation of comprehensive carbohydrate-based combinatorial library programs. In addition, details of oligosaccharide and glycoconjugate libraries constructed using both solid phase and solution phase strategies are presented.

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收藏

页码：75 / 94

页数：20

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