Integrin-protein kinase C relationships

被引:23
作者
Ivaska, J
Kermorgant, S
Whelan, R
Parsons, M
Ng, T
Parker, PJ
机构
[1] London Res Inst, London WC2A 3PX, England
[2] St Thomas Hosp, GKT Sch Med, Dept Canc Res, London SE1 7EH, England
[3] Univ London Kings Coll, Randall Ctr, London SE1 1UL, England
关键词
adherence; migration; phosphorylation;
D O I
10.1042/bst0310090
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The integrins have an ability to interact with extracellular matrix proteins to confer adhesive and motile properties on cells. The means by which these activities operate and the manner in which they are integrated with cell functions is of particular relevance to many biological processes. in the present paper, the developing understanding of the bi-directional relationship between the protein kinase C family of signal transducers and integrins is discussed.
引用
收藏
页码:90 / 93
页数:4
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