The effect of molecular organisation in DNA oligomers studied by femtosecond fluorescence spectroscopy

被引：67

作者：

Markovitsi, D ^{[1
]}

Sharonov, A ^{[1
]}

Onidas, D ^{[1
]}

Gustavsson, T ^{[1
]}

机构：

[1] CEA Saclay, Lab Francis Perrin, CNRS, URA 2453,CEA,DSM,DRECAM,SPAM, F-91191 Gif Sur Yvette, France

来源：

CHEMPHYSCHEM | 2003年 / 4卷 / 03期

关键词：

DNA; femtobiology; fluorescence; nucleotides; time-resolved spectroscopy;

D O I：

10.1002/cphc.200390050

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Organisation lengthens life! The first fluorescence investigation of DNA oligomers performed with femtosecond resolution revealed that organisation of nucleotides into single strands, and further into double strands, makes the fluorescence decays slower and slower (see graph). This is important because a longer lifetime increases the reactivity of the excited states and, thus, the probability of inducing damage to the double helix.

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页码：303 / +

页数：4

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