Update and future of hormonal therapy in acne

被引:60
作者
Thiboutot, D
Chen, WC
机构
[1] Penn State Univ, Milton S Hershey Med Ctr, Div Dermatol, Dept Dermatol, Hershey, PA 17033 USA
[2] Natl Cheng Kung Univ, Coll Med, Dept Dermatol, Tainan 70101, Taiwan
关键词
acne; hormone; androgens; steroid; oral contraceptive;
D O I
10.1159/000067823
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 ;
摘要
Hormonal therapy is an important component in the treatment of women with acne who may or may not have elevated serum androgens. The mainstays of hormonal therapy include oral contraceptives and antiandrogens such as cyproterone acetate, flutamide or spironolactone. Recent research over the past several years has unraveled some of the details regarding the way that the skin and sebaceous glands synthesize and metabolize hormones. The knowledge gained from this work may provide an impetus for future drug discovery in the hormonal treatment of acne and lead to improvements in the care of our patients with acne. Copyright (C) 2003 S. Karger AG, Basel.
引用
收藏
页码:57 / 67
页数:11
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