Synthesis of optically active substituted 3-fluoropiperidines from prolinols by using DAST

被引：40

作者：

Dechamps, Ingrid ^{[1
]}

Gomez Pardo, Domingo ^{[1
]}

Cossy, Janine ^{[1
]}

机构：

[1] Ecole Super Phys & Chim Ind Ville Paris, CNRS, Chim Organ Lab, F-75231 Paris 05, France

来源：

SYNLETT | 2007年 / 02期

关键词：

ring expansion; fluorine; rearrangements; piperidine; aziridinium;

D O I：

10.1055/s-2007-967989

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

The treatment of optically active prolinols with DAST produces optically active 3-fluoropiperidines via aziridinium intermediates.

引用

页码：263 / 267

页数：5

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