Composite organic-inorganic nanoparticles (COINs) with chemically encoded optical signatures

被引：221

作者：

Su, X

Zhang, J

Sun, L

Koo, TW

Chan, S

Sundararajan, N

Yamakawa, M

Berlin, AA

机构：

[1] Intel Corp, Biotechnol Res Grp, Intel Res, Santa Clara, CA 95054 USA

[2] Intel Corp, CTM, Santa Clara, CA 95054 USA

来源：

NANO LETTERS | 2005年 / 5卷 / 01期

关键词：

D O I：

10.1021/nl0484088

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

To obtain a coding system for multiplex detection, we have developed a method to synthesize a new type of nanomaterial called composite organic-inorganic nanoparticles (COINs). The method allows the incorporation of a broad range of organic compounds into COINs to produce surface enhanced Raman scattering (SERS)-like spectra that are richer in variety than fluorescence-based signatures. Preliminary data suggest that COINs can be used as Raman tags for multiplex and ultrasensitive detection of biomolecules.

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页码：49 / 54

页数：6

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