Call of the wild: antibiotic resistance genes in natural environments

被引:1602
作者
Allen, Heather K. [1 ,2 ,3 ]
Donato, Justin [1 ,2 ]
Wang, Helena Huimi [4 ]
Cloud-Hansen, Karen A. [1 ,2 ]
Davies, Julian [4 ]
Handelsman, Jo [5 ]
机构
[1] Univ Wisconsin Madison, Dept Bacteriol, Madison, WI 53706 USA
[2] Univ Wisconsin Madison, Dept Plant Pathol, Madison, WI 53706 USA
[3] Univ Wisconsin Madison, Microbiol Doctoral Training Program, Madison, WI 53706 USA
[4] Univ British Columbia, Dept Microbiol & Immunol, Vancouver, BC V6T 1Z3, Canada
[5] Yale Univ, Dept Mol Cellular & Dev Biol, New Haven, CT 06520 USA
基金
美国国家卫生研究院;
关键词
HEAVY-METAL RESISTANCE; FUNGUS-GROWING ANTS; ESCHERICHIA-COLI; ANTIMICROBIAL RESISTANCE; STAPHYLOCOCCUS-AUREUS; BETA-LACTAMASES; HIGH PREVALENCE; SOIL BACTERIA; CHLORAMPHENICOL; INTEGRONS;
D O I
10.1038/nrmicro2312
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Antibiotic-resistant pathogens are profoundly important to human health, but the environmental reservoirs of resistance determinants are poorly understood. The origins of antibiotic resistance in the environment is relevant to human health because of the increasing importance of zoonotic diseases as well as the need for predicting emerging resistant pathogens. This Review explores the presence and spread of antibiotic resistance in non-agricultural, non-clinical environments and demonstrates the need for more intensive investigation on this subject.
引用
收藏
页码:251 / 259
页数:9
相关论文
共 101 条
[81]   Human intestinal bacteria as reservoirs for antibiotic resistance genes [J].
Salyers, AA ;
Gupta, A ;
Wang, YP .
TRENDS IN MICROBIOLOGY, 2004, 12 (09) :412-416
[82]   Why are antibiotic resistance genes so resistant to elimination? [J].
Salyers, AA ;
AmabileCuevas, CF .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1997, 41 (11) :2321-2325
[83]   A global perspective on the use, sales, exposure pathways, occurrence, fate and effects of veterinary antibiotics (VAs) in the environment [J].
Sarmah, Ajit K. ;
Meyer, Michael T. ;
Boxall, Alistair B. A. .
CHEMOSPHERE, 2006, 65 (05) :725-759
[84]   More than a signal: non-signaling properties of quorum sensing molecules [J].
Schertzer, Jeffrey W. ;
Boulette, Megan L. ;
Whiteley, Marvin .
TRENDS IN MICROBIOLOGY, 2009, 17 (05) :189-195
[85]   Review of the Occurrence of Anti-infectives in Contaminated Wastewaters and Natural and Drinking Waters [J].
Segura, Pedro A. ;
Francois, Matthieu ;
Gagnon, Christian ;
Sauve, Sebastien .
ENVIRONMENTAL HEALTH PERSPECTIVES, 2009, 117 (05) :675-684
[86]  
Serrano P.H., 2005, RESPONSIBLE USE ANTI
[87]   Dissemination of multildrug-resistant bacteria into the Arctic [J].
Sjolund, Maria ;
Bonnedahl, Jonas ;
Hernandez, Jorge ;
Bengtsson, Stina ;
Cederbrant, Gunilla ;
Pinhassi, Jarone ;
Kahlmeter, Gunnar ;
Olsen, Bjoern .
EMERGING INFECTIOUS DISEASES, 2008, 14 (01) :70-72
[88]   Effect of human vicinity on antimicrobial resistance and integrons in animal faecal Escherichia coli [J].
Skurnik, David ;
Ruimy, Raymond ;
Andremont, Antoine ;
Amorin, Christine ;
Rouquet, Pierre ;
Picard, Bertrand ;
Denamur, Erick .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2006, 57 (06) :1215-1219
[89]   R FACTOR INFECTION OF ESCHERICHIA COLI LYOPHILIZED IN 1946 [J].
SMITH, DH .
JOURNAL OF BACTERIOLOGY, 1967, 94 (06) :2071-&
[90]  
Song JS, 2006, J MICROBIOL, V44, P126