Expression analysis of classic and non-classic HLA molecules before interferon alfa-2b treatment of melanoma

被引：95

作者：

Wagner, SN ^{[1
]}

Rebmann, V

Willers, CP

Grosse-Wilde, H

Goos, M

机构：

[1] Univ Essen Gesamthsch, Sch Med, Dept Dermatol, D-45122 Essen, Germany

[2] Univ Essen Gesamthsch, Sch Med, Dept Immunol, D-45122 Essen, Germany

来源：

LANCET | 2000年 / 356卷 / 9225期

关键词：

D O I：

10.1016/S0140-6736(00)02486-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Individual predictive clinical, immunological, or molecular features for definition of patients with lymph-node-positive melanoma who do not benefit from adjuvant postsurgery high-dose interferon alfa treatment are lacking. Expression analysis of classic and non-classic HLA molecules on melanoma cells metastatic to the locoregional lymph node may help select these patients before treatment.

引用

页码：220 / 221

页数：2

共 5 条

[1] ROLE OF INTERFERONS AND OTHER CYTOKINES IN THE REGULATION OF THE IMMUNE-RESPONSE [J].

BELARDELLI, F .

APMIS, 1995, 103 (03) :161-179

[2] Implications for immunosurveillance of altered HLA class I phenotypes in human tumours [J].

Garrido, F ;

RuizCabello, F ;

Cabrera, T ;

PerezVillar, JJ ;

LopezBotet, M ;

DugganKeen, M ;

Stern, PL .

IMMUNOLOGY TODAY, 1997, 18 (02) :89-95

[3]

KIRKWOOD JM, 1998, 23 ANN C EUR SOC MED

[4]

Paul P, 1999, CANCER RES, V59, P1954

[5] HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance [J].

Paul, P ;

Rouas-Freiss, N ;

Khalil-Daher, I ;

Moreau, P ;

Riteau, B ;

Le Gal, FA ;

Avril, MF ;

Dausset, J ;

Guillet, JG ;

Carosella, ED .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (08) :4510-4515

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