Synthesis, reaction, and structure of chiral N-methyl-2-oxazolidinones from 3-ethoxy-6-(N-methyl-N-tert-butoxycarbonyl)amino-2,4-hexadienoates

被引：6

作者：

Kawano, T ^{[1
]}

Negoro, K ^{[1
]}

Ueda, I ^{[1
]}

机构：

[1] OSAKA UNIV,INST SCI & IND RES,IBARAKI,OSAKA 567,JAPAN

来源：

TETRAHEDRON LETTERS | 1997年 / 38卷 / 47期

关键词：

D O I：

10.1016/S0040-4039(97)10199-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

N-methyl-2-oxazolidinones (4) are obtained stereo-and regio-selectively when 3-ethoxy-6-(N-methyl-N-tert-butoxycarbonyl)amino-2,4-hexadienoates (1) are treated with concentrated sulfuric acid (1.0 equiv.) supported on silicagel in dichloromethane at 0 degrees C. 4 were shown to be intermediates for the construction of N-methylpyrrole ring. The structure and properties of 4 and related compounds are also described. (C) 1997 Elsevier Science Ltd.

引用

页码：8219 / 8222

页数：4

共 11 条

[1] CHIRAL OXAZOLIDINONES FROM N-BOC DERIVATIVES OF BETA-AMINO ALCOHOLS - EFFECT OF A N-METHYL SUBSTITUENT ON REACTIVITY AND STEREOSELECTIVITY [J].