Batch and continuous cultivation of Anaerobiospirillum succiniciproducens for the production of succinic acid from whey

被引：85

作者：

Lee, PC ^{[1
]}

Lee, WG ^{[1
]}

Kwon, S ^{[1
]}

Lee, SY ^{[1
]}

Chang, HN ^{[1
]}

机构：

[1] Korea Adv Inst Sci & Technol, Dept Chem Engn, Yusong Gu, Taejon 305701, South Korea

来源：

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY | 2000年 / 54卷 / 01期

关键词：

D O I：

10.1007/s002530000331

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Batch and continuous cultivation of Anaero-biospirillum succiniciproducens were systematically studied for the production of succinic acid from whey. Addition of 2.5 g l(-1) yeast extract and 2.5 g l(-1) polypeptone per 10 g l(-1) whey was most effective for succinic acid production from both treated and nontreated whey. When 20 g l(-1) nontreated whey and 7 g l(-1) glucose were used as cosubstrates, the yield and productivity of succinic acid reached at the end of fermentation were 95% and 0.46 g (1 h)(-1), respectively. These values were higher than those obtained using nontreated whey alone [93% and 0.24 g (1 h)(-1) for 20 g l(-1) whey]. Continuous fermentation of A. succiniciproducens at an optimal dilution rate resulted in the production of succinic acid with high productivity [1.35 g (1 h)(-1)], high conversion yield (93%), and higher ratio of succinic acid to acetic acid (5.1:1) from nontreated whey.

引用

页码：23 / 27

页数：5

共 21 条

[1] PRODUCTION OF 2,3-BUTYLENE GLYCOL FROM WHEY BY KLEBSIELLA-PNEUMONIAE AND ENTEROBACTER-AEROGENES [J].

BARRETT, EL ;

COLLINS, EB ;

HALL, BJ ;

MATOI, SH .

JOURNAL OF DAIRY SCIENCE, 1983, 66 (12) :2507-2514

[2]

CHIARINI L, 1992, APPL MICROBIOL BIOT, V36, P461, DOI 10.1007/BF00170183

[3] PRODUCTION OF PROPIONIC-ACID FROM WHEY PERMEATE BY SEQUENTIAL FERMENTATION, ULTRAFILTRATION, AND CELL RECYCLING [J].

COLOMBAN, A ;

ROGER, L ;

BOYAVAL, P .

BIOTECHNOLOGY AND BIOENGINEERING, 1993, 42 (09) :1091-1098

[4]

Datta R, 1992, US Patent, Patent No. [5143833, 5,143,833]

[5] ANAEROBIOSPIRILLUM, A NEW GENUS OF SPIRAL-SHAPED BACTERIA [J].

DAVIS, CP ;

CLEVEN, D ;

BROWN, J ;

BALISH, E .

INTERNATIONAL JOURNAL OF SYSTEMATIC BACTERIOLOGY, 1976, 26 (04) :498-504

[6]

Glassner DA, 1992, US Patent, Patent No. [5143834, 5,143,834]

[7]

GOTTSCHALK G, 1986, BACTERIAL METABOLISM, P242

[8] WHEY UTILIZATION AND WHEY PRODUCTS [J].

KOSIKOWSKI, FV .

JOURNAL OF DAIRY SCIENCE, 1979, 62 (07) :1149-1160

[9] METHODOLOGY FOR EVALUATING THE ECONOMICS OF BIOLOGICALLY PRODUCING CHEMICALS AND MATERIALS FROM ALTERNATIVE FEEDSTOCKS [J].

LANDUCCI, R ;

GOODMAN, B ;

WYMAN, C .

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 1994, 45-6 :677-696

[10] Effects of medium components on the growth of Anaerobiospirillum succiniciproducens and succinic acid production [J].

Lee, PC ;

Lee, WG ;

Lee, SY ;

Chang, HN .

PROCESS BIOCHEMISTRY, 1999, 35 (1-2) :49-55

← 1 2 3 →