Determination of selected persistent organochlorine pollutants in human serum by solid-phase disk extraction and dual-columin capillary gas chromatography with electron capture detection

被引：9

作者：

Covaci, A ^{[1
]}

Pauwels, A ^{[1
]}

Schepens, P ^{[1
]}

机构：

[1] Univ Antwerp, Toxicol Ctr, B-2610 Wilrijk, Belgium

来源：

INTERNATIONAL JOURNAL OF ENVIRONMENTAL ANALYTICAL CHEMISTRY | 2000年 / 76卷 / 03期

关键词：

PCB; persistent organochlorine pollutants; human serum; solid phase disk extraction; dual column; electron capture detector;

D O I：

10.1080/03067310008034129

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

An improved clean-up method by solid-phase disk extraction was developed to isolate and concentrate trace levels of POPs (persistent organochlorine pollutants) in human serum prior to gas chromatography with electron capture detection on two different capillary columns, providing an improved selectivity. An Empore(TM) C-18 bonded silica extraction disk cartridge is used for the initial extraction and enrichment of the analytes. Subsequent clean-up is achieved by concentrated sulphuric acid and silica gel adsorption chromatography, Recoveries for selected POPs are ranging from 62 to 74% and a good reproducibility (RSD < 14%) is demonstrated. Human samples analysed under these conditions, show a similar relative concentration profile.

引用

页码：167 / 178

页数：12

共 26 条

[1] Profiles of great lakes critical pollutants: A sentinel analysis of human blood and urine [J].