On-chip surface-enhanced Raman scattering detection using integrated liquid-core waveguides

被引：76

作者：

Measor, Philip

Seballos, Leo

Yin, Dongliang

Zhang, Jin Z.

Lunt, Evan J.

Hawkins, Aaron R.

Schmidt, Holger

机构：

[1] Univ Calif Santa Cruz, Sch Engn, Santa Cruz, CA 95064 USA

[2] Univ Calif Santa Cruz, Dept Chem & Biochem, Santa Cruz, CA 95064 USA

[3] Brigham Young Univ, Dept Elect & Comp Engn, Provo, UT 84604 USA

来源：

APPLIED PHYSICS LETTERS | 2007年 / 90卷 / 21期

基金：

美国国家科学基金会; 美国国家卫生研究院;

关键词：

D O I：

10.1063/1.2742287

中图分类号：

O59 [应用物理学];

学科分类号：

摘要：

The authors demonstrate surface-enhanced Raman scattering (SERS) detection on an optofluidic chip. Interconnected solid- and liquid-core antiresonant reflecting optical waveguides (ARROWs) form a planar beam geometry that allows for high mode intensities along microfluidic channels containing molecules optimized for SERS. The excitation power and concentration dependence of SERS from rhodamine 6G (R6G) molecules adsorbed to silver nanoparticles were systematically studied. The data can be described by a model that takes into account the microphotonic structure. Detection sensitivity to a minimum concentration of 30 nM is found, demonstrating the suitability of ARROW-based optofluidic chips for high sensitivity detection with molecular specificity. (c) 2007 American Institute of Physics.

引用

页数：3

共 21 条

[1] Fabrication of hollow waveguides with sacrificial aluminum cores [J].