Unusual pH-dependent polarity changes in PAMAM dendrimers: Evidence for pH-responsive conformational changes

被引：186

作者：

Chen, W

Tomalia, DA

Thomas, JL ^{[1
]}

机构：

[1] Columbia Univ, Dept Chem Engn & Appl Chem, New York, NY 10027 USA

[2] Univ Michigan, Ctr Biol Nanotechnol, Ann Arbor, MI 48109 USA

来源：

MACROMOLECULES | 2000年 / 33卷 / 25期

关键词：

D O I：

10.1021/ma000791p

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The polarity-responsive probe 5-(dimethylamino)-1-naphthalenesulfonic acid (DNS) was used to explore changes in dendrimer structure that may occur with pH titration. It was found that the fluorescence quantum yield and Stokes shift of DNA vary with solvent polarity and to a lesser extent with solvent microviscosity. Polar solvents stabilized a twisted intramolecular charger transfer (TICT) species.

引用

页码：9169 / 9172

页数：4

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