Acute neutropenia decreases inflammation associated with murine vaginal candidiasis but has no effect on the course of infection

被引：52

作者：

Black, CA

Eyers, FM

Russell, A

Dunkley, ML

Clancy, RL

Beagley, KW ^{[1
]}

机构：

[1] Univ Newcastle, Callaghan, NSW 2308, Australia

[2] Australian Inst Mucosal Immunol, Newcastle, NSW 2300, Australia

来源：

INFECTION AND IMMUNITY | 1998年 / 66卷 / 03期

关键词：

D O I：

10.1128/IAI.66.3.1273-1275.1998

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

We have used a mouse model of vaginal candidiasis to determine the effect of neutrophil depletion on (a) the clearance of Candida albicans and (b) the degree of inflammation associated with infection. No differences in recoverable yeast number or rate of clearance were observed between normal and neutrophil-depleted mice; however, vaginal inflammation was significantly decreased in neutrophil-depleted animals.

引用

页码：1273 / 1275

页数：3

共 16 条

[1] CANDIDA AND CANDIDIASIS .1. CULTURAL CONDITIONS, EPIDEMIOLOGY AND PATHOGENESIS [J].