Concise synthesis of (±)-horsfiline and (±)-coerulescine by tandem cyclisation of iodoaryl alkenyl azides

被引：80

作者：

Lizos, DE ^{[1
]}

Murphy, JA ^{[1
]}

机构：

[1] Univ Strathclyde, Dept Pure & Appl Chem, Glasgow G1 1XL, Lanark, Scotland

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2003年 / 1卷 / 01期

关键词：

D O I：

10.1039/b208114h

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A brief, efficient and economical synthesis of the spiropyrrolidinyloxindoles, horsfiline and coerulescine, has been achieved, starting from itaconic acid and, respectively, p-anisidine or o-iodoaniline. Tandem radical cyclisation of iodoaryl alkenyl azides is the key step in both syntheses.

引用

页码：117 / 122

页数：6

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