ToxoDB:: accessing the Toxoplasma gondii genome

被引:155
作者
Kissinger, JC
Gajria, B
Li, L
Paulsen, IT
Roos, DS [1 ]
机构
[1] Univ Georgia, Dept Genet, Ctr Trop & Emerging Global Dis, Athens, GA 30602 USA
[2] Univ Penn, Dept Biol, Philadelphia, PA 19104 USA
[3] Inst Genom Res, Rockville, MD 20850 USA
基金
美国国家卫生研究院;
关键词
D O I
10.1093/nar/gkg072
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
ToxoDB (http://ToxoDB.org) provides a genome resource for the protozoan parasite Toxoplasma gondii. Several sequencing projects devoted to T. gondii have been completed or are in progress: an EST project (http://genome.wustl.edu/est/index.php?toxoplasma=1), a BAC clone end-sequencing project (http://www.sanger.ac.uk/Projects/T_gondii/) and an 8X random shotgun genomic sequencing project (http://www.tigr.org/tdb/e2k1/tga1/). ToxoDB was designed to provide a central point of access for all available T. gondii data, and a variety of data mining tools useful for the analysis of unfinished, un-annotated draft sequence during the early phases of the genome project. In later stages, as more and different types of data become available (microarray, proteomic, SNP, QTL, etc.) the database will provide an integrated data analysis platform facilitating user-defined queries across the different data types.
引用
收藏
页码:234 / 236
页数:3
相关论文
共 11 条
[1]
Analysis of apicomplexan parasites [J].
Ajioka, JW .
METHODS-A COMPANION TO METHODS IN ENZYMOLOGY, 1997, 13 (02) :79-80
[2]
Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the apicomplexa [J].
Ajioka, JW ;
Boothroyd, JC ;
Brunk, BP ;
Hehl, A ;
Hillier, L ;
Manger, ID ;
Marra, M ;
Overton, GC ;
Roos, DS ;
Wan, KL ;
Waterston, R ;
Sibley, LD .
GENOME RESEARCH, 1998, 8 (01) :18-28
[3]
PlasmoDB:: the Plasmodium genome resource.: An integrated database providing tools for accessing, analyzing and mapping expression and sequence data (both finished and unfinished) [J].
Bahl, A ;
Brunk, B ;
Coppel, RL ;
Crabtree, J ;
Diskin, SJ ;
Fraunholz, MJ ;
Grant, GR ;
Gupta, D ;
Huestis, RL ;
Kissinger, JC ;
Labo, P ;
Li, L ;
McWeeney, SK ;
Milgram, AJ ;
Roos, DS ;
Schug, J ;
Stoeckert Jr, CJ .
NUCLEIC ACIDS RESEARCH, 2002, 30 (01) :87-90
[4]
K2/Kleisli and GUS: Experiments in integrated access to genomic data sources [J].
Davidson, SB ;
Crabtree, J ;
Brunk, BP ;
Schug, J ;
Tannen, V ;
Overton, GC ;
Stoeckert, CJ .
IBM SYSTEMS JOURNAL, 2001, 40 (02) :512-531
[5]
DUBEY JP, 1997, PARASITIC PROTOZOA, V3, P101
[6]
Gene discovery in Plasmodium chabaudi by genome survey sequencing [J].
Janssen, CS ;
Barrett, MP ;
Lawson, D ;
Quail, MA ;
Harris, D ;
Bowman, S ;
Phillips, RS ;
Turner, CMR .
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2001, 113 (02) :251-260
[7]
TOXOPLASMIC ENCEPHALITIS IN AIDS [J].
LUFT, BJ ;
REMINGTON, JS .
CLINICAL INFECTIOUS DISEASES, 1992, 15 (02) :211-222
[8]
REMINGTON JS, 1989, INFECT DIS, P89
[9]
Roos DS, 2000, BIOLOGY OF PARASITISM, P143
[10]
CONSTRUCTION OF A MOLECULAR KARYOTYPE FOR TOXOPLASMA-GONDII [J].
SIBLEY, LD ;
BOOTHROYD, JC .
MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1992, 51 (02) :291-300